Pharmacokinetics Vs Pharmacodynamic Math
Introduction to pharmacokinetics and pharmacodynamics pharmacokinetics is currently defined as the study of the time course of drug absorption distribution metabo lism and excretion.
Pharmacokinetics vs pharmacodynamic math. Pharmacodynamics takes into account the complex interactions between the drug the human body and then the pathogen that might be causing. The drug entering circulation. How to remember pharmacokinetics and pharmacodynamics. Pharmacokinetics is how a body processes a drug.
Clinical pharmacokinetics is the application of pharmacokinetic principles to the safe and effective therapeutic management of drugs in an individual patient. Simply pharmacokinetics is the body s action on the drug or alteration of a drug by the body. Pharmacokinetics consists of the following. You will learn more about.
It s really mostly focused on the drug and the body. Patients were stratified according to creatinine clearance clcr into different groups of normal clcr 80 ml the pharmacokinetics and pharmacodynamics of zoledronic acid in cancer patients with varying. While pharmacodynamics is the drug action on the body. So how the drug is absorbed how it s distributed throughout the body where it s distributed how you metabolize the drug and then eliminate it.
To elaborate on these is the objective of this chapter. Interference with drug effects on receptor function interference with a physiological control process and additive or opposing physiological effects. An experiment in drug development consists of two parts. Delve deeper into this topic by using the lesson titled pharmacokinetics vs.
On the other hand pharmacodynamics is what the drug does to the body. Tulkens unite de pharmacologie cellulaire et mole culaire uni ersite catholique de lou ain ucl 73 70 a enue e. Pharmacokinetics is what the body does to the drug while pharmacodynamics is what the drug does to the body. Pharmacokinetics vs pharmacodynamics.
Interactions between drugs can be classified as pharmacokinetic or pharmacodynamic. The pharmacokinetics pk describes the time course of drugs. So to remember it easily pharmacodynamics is the effect of the drug on the body and therefore the pharmacokinetics mean what the body does. The pharmacodynamic interactions of drug on drug can be divided into three broad groups.
6 example of pharmacokinetics and pharmacodynamics. An open label pharmacokinetic and pharmacodynamic study of zoledronic acid zometa was performed in 19 cancer patients with bone metastases and known varying levels of renal function. It is believed that by better understanding of the relationship between pk and pd one can shed light on situations where one or the other needs to be. Pharmacokinetics and pharmacodynamics f.
Which greek words each term is derived from what the words enteral and. Primary goals of clinical pharmacokinetics include.