Multiple Myeloma Risk Factors Math
People with a history of monoclonal gammopathy of undetermined significance mgus can also be at an increased risk of developing the disease.
Multiple myeloma risk factors math. Pmr proportionate mortality ratio. Rr relative risk. Sir standardized incidence ratio. Hl hodgkin lymphoma.
Ci confidence interval. For multiple myeloma however the primary modifiable risk factors involve exposure to environmental substances usually related to a person s occupation. A plasma cell is a type of white blood cell that makes antibodies to help the body fight infection. Different cancers have different risk factors.
History of monoclonal gammopathy of undetermined significance mgus mgus is a plasma cell disorder that has the potential to develop into multiple myeloma. Bmpc 20 m protein 2 g dl and flcr 20 at diagnosis can be. Nhl non hodgkin lymphoma. Many of the known and possible risk factors for mgus are the same as for multiple myeloma.
International agency for research on cancer iarc classifies the role of this risk factor in cancer development 14 of myeloma cases in the uk are caused by overweight and obesity myeloma risk is 12 higher per 5 unit body mass index bmi increment an umbrella study of meta analyses showed myeloma risk increases in males and females for both overweight and obesity categories a meta. For example exposing skin to strong sunlight is a risk factor for skin cancer. Risk factors for multiple myeloma university of texas m d. Low risk none of the three risk factors.
Mm multiple myeloma. Exposure to radiation is another factor that can increase the risk of multiple myeloma. Obesity and family history are some common risk factors seen in most cases of multiple myeloma. Risk factors for multiple myeloma.
Multiple myeloma research foundation. There is convincing evidence that the following factors increase your risk for multiple myeloma. Exposure to chemicals or radiation exposure to chemicals such as those in asbestos and pesticides as well as exposure to benzene a substance present in rubber manufacturing may pose an increased risk of developing myeloma. Smr standardized mortality ratio.
What causes multiple myeloma and what increases your risk. And high risk 2 of the three risk factors. We stratified patients into three groups. Smoking is a risk factor for lung cancer and many other cancers.
Or odds ratio. The median ttp for low intermediate and high risk groups were 110 68 and 29 months respectively p 0 0001. Multiple myeloma prevention and screening.